Aims & Scope
The Journal of Clinical Case Reports and Images (JCCI) publishes comprehensive clinical documentation, medical imaging analysis, and case-based research that advances evidence-based medicine through systematic reporting of clinical observations, diagnostic findings, and treatment outcomes across all medical specialties.
Core Research Domains
Clinical Case Reports Tier 1
Detailed documentation of unique clinical presentations, rare diseases, unusual complications, and novel diagnostic or therapeutic approaches.
- Rare disease presentations and atypical manifestations
- Unusual complications of common conditions
- Novel diagnostic approaches and imaging findings
- Innovative treatment strategies and outcomes
- Adverse drug reactions and medication interactions
- Diagnostic challenges and clinical reasoning
"Atypical presentation of acute appendicitis mimicking ovarian torsion: A case report with ultrasound and CT correlation"
Medical Imaging & Diagnostics Tier 1
High-quality medical images with detailed clinical correlation, diagnostic interpretation, and educational value for healthcare professionals.
- Radiological imaging (CT, MRI, X-ray, ultrasound)
- Pathological imaging and histopathology
- Endoscopic and surgical imaging
- Dermatological and clinical photography
- Diagnostic imaging pearls and pitfalls
- Image-guided interventions and procedures
"MRI findings in posterior reversible encephalopathy syndrome (PRES): A case series with diffusion-weighted imaging correlation"
Clinical Case Series Tier 1
Systematic analysis of multiple cases sharing common features, providing insights into disease patterns, treatment responses, and clinical outcomes.
- Retrospective case series analysis
- Treatment outcome comparisons
- Disease pattern recognition and trends
- Complication rates and risk factors
- Diagnostic accuracy studies
- Quality improvement initiatives
"Clinical outcomes of COVID-19 patients with pre-existing cardiovascular disease: A single-center case series of 150 patients"
Multidisciplinary Clinical Research Tier 1
Clinical studies spanning multiple specialties, including internal medicine, surgery, pediatrics, obstetrics, emergency medicine, and allied health sciences.
- Cross-specialty clinical collaborations
- Multidisciplinary team approaches
- Integrated care pathways and protocols
- Specialty-specific case reports (cardiology, neurology, oncology, etc.)
- Surgical techniques and perioperative care
- Emergency medicine and critical care cases
"Multidisciplinary management of complex pelvic trauma: A case report involving orthopedic, vascular, and urological interventions"
Secondary Focus Areas
Clinical Practice Guidelines
Evidence-based recommendations for diagnosis, treatment, and management of specific clinical conditions derived from case-based evidence.
Medical Education
Teaching cases, clinical reasoning exercises, and educational materials that enhance medical training and continuing professional development.
Quality Improvement
Case-based quality improvement initiatives, patient safety reports, and healthcare delivery optimization studies.
Telemedicine & Digital Health
Clinical cases involving telehealth consultations, remote monitoring, digital diagnostics, and technology-enabled care delivery.
Global Health
Clinical cases from diverse geographic regions, resource-limited settings, tropical diseases, and international health challenges.
Pharmacotherapy
Clinical pharmacology cases, drug efficacy reports, medication management strategies, and pharmaceutical interventions.
Emerging & Selective Areas
Artificial Intelligence in Clinical Practice
Cases demonstrating AI-assisted diagnosis, machine learning applications in clinical decision-making, and computational medicine.
Precision Medicine
Personalized treatment approaches based on genetic profiling, biomarker analysis, and individualized therapeutic strategies.
Regenerative Medicine
Clinical applications of stem cell therapy, tissue engineering, and regenerative approaches with documented patient outcomes.
One Health Approach
Clinical cases at the human-animal-environment interface, zoonotic diseases, and environmental health impacts on clinical practice.
Out of Scope
- Basic Science Research: Laboratory studies, molecular biology, or biochemical research without direct clinical correlation or patient outcomes. Rationale: JCCI focuses on clinical application rather than fundamental research.
- Animal Studies: Pre-clinical animal models, veterinary medicine, or animal research unless directly relevant to human clinical translation with documented human cases. Rationale: Journal scope is limited to human clinical medicine.
- Purely Theoretical Models: Mathematical modeling, computational simulations, or theoretical frameworks without clinical validation or real-world patient data. Rationale: Emphasis on evidence-based clinical practice.
- Systematic Reviews & Meta-Analyses: Comprehensive literature reviews or meta-analyses without original case data. Rationale: Journal prioritizes original clinical observations and case reports.
- Opinion Pieces & Editorials: Commentary articles, personal opinions, or editorial perspectives without supporting case evidence. Rationale: Focus on documented clinical cases rather than subjective viewpoints.
Article Types & Priorities
Priority 1: Fast-Track Review
Expedited peer review within 14-21 days for high-impact clinical contributions.
Priority 2: Standard Review
Standard peer review within 28-42 days for valuable clinical contributions.
Priority 3: Selective Consideration
Considered on a case-by-case basis; must demonstrate exceptional clinical value or educational merit.
Editorial Standards & Requirements
Reporting Guidelines
- CARE Guidelines for case reports
- STROBE for observational studies
- CONSORT for clinical trials
- PRISMA for systematic reviews
- STARD for diagnostic accuracy
Ethical Requirements
- IRB/Ethics committee approval
- Patient informed consent
- Privacy protection (HIPAA compliance)
- Declaration of conflicts of interest
- Helsinki Declaration adherence
Data & Transparency
- Raw data availability statement
- Clinical trial registration (if applicable)
- Funding source disclosure
- Author contribution statements
- Reproducibility documentation
Image Quality Standards
- Minimum 300 DPI resolution
- DICOM format for radiological images
- Proper anonymization of patient data
- Clear labeling and annotations
- High-quality clinical photography
Preprint Policy
- Preprints accepted (medRxiv, bioRxiv)
- Must disclose preprint DOI
- No duplicate publication
- Version control documentation
- Post-publication updates allowed
Peer Review Process
- Single-blind peer review
- Minimum two expert reviewers
- Statistical review when applicable
- Ethics review for sensitive cases
- Post-publication peer review option
Publication Metrics & Performance
Our Commitment to Authors
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