Dr. Feng Ding

Address:

Research Associate Professor, School of Basic Medical Sciences
Wenzhou Medical University, Wenzhou 325035, China

Research Interests:

• Multidrug Resistance (MDR) and Efflux Transporters
• Bacterial Pathogenesis (Mycobacterium tuberculosis)
• Nanobiochemistry and Nanosensors
• Fluorescence Spectroscopy and Super-resolution Imaging
• Antimicrobial Therapies and Drug Carriers

Biography:

Dr. Feng Ding is a Research Associate Professor specializing in Microbiology, Immunology, and Nanobiochemistry. His research focuses on the molecular mechanisms and development of countermeasures against multidrug resistance (MDR), particularly in pathogens like Mycobacterium tuberculosis. Dr. Ding utilizes advanced nanoparticle-based probes and sensors for super-resolution, real-time imaging of host-bacteria interactions and MDR transporters. His work is dedicated to developing novel, cost-effective therapeutic strategies and nanocarriers to combat infectious diseases and enhance drug efficacy.
 

Education Details

• Ph.D. (Biomedical Science/Chemistry), Old Dominion University, USA (2008–2013)
• M.S. (Biochemistry/Molecular Biology), Second Military Medical University, China (2002–2006)
• B.S. (Biotechnology), Soochow University, China (1997–2001)

Professional Background

• Research Associate Professor (Current), School of Basic Medical Sciences, Wenzhou Medical University, China (since 2016).
• Postdoctoral Research Fellow, Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, USA (2014–2015).
• Research Associate (Malaria Vaccine Development), Second Military Medical University, China (2002–2007).

Achievements

• Pioneered the application of dark-field optical microscopy and far-field photostable optical nanoscopy using nanoparticle probes to study Multidrug Resistance (MDR) efflux functions in real-time.
• Involved in the Phase I clinical trial study of a malaria vaccine candidate.
   

Current Research Projects

Dr. Ding's work focuses on combating antibiotic resistance and enhancing diagnostics:

• Developing novel molecular probes and nano-assays for the accurate detection and real-time imaging of biological processes.
• Deciphering the molecular mechanisms by which M. tuberculosis intervenes with host cell processes (autophagy, apoptosis).
• Designing and testing new nanoparticle-based systems to overcome multidrug resistance in pathogens like P. aeruginosa and M. tuberculosis.
   

Academic Profiles of Dr. Feng Ding

Explore his academic and professional presence across trusted platforms.

• ResearchGate

Publications:

Dr. Ding's research established his profile through work on nanobiochemistry and multidrug resistance.
 

1. Ding, F., Li, Y., et al. (2015). Single-molecule detection of Mg2+ concentration on the surface of lipid bilayers with the fluorescence-labeled Au nanorods. Analytical Chemistry, 87(23), 11624–11631.
2. Zhang, J., Ding, F., Chen, F., Wang, F., & Li, Z. (2014). Single-molecule detection of the catalytic reaction rate of multidrug transporter BmrA using gold nanorods. Angewandte Chemie International Edition, 53(31), 8196–8201.
3. Ding, F., Zhang, J., Chen, F., Wang, F., Li, Z., & Gao, D. (2014). Size-dependent inhibitory effects of silver nanoparticles with antibiotics conjugated on the growth of bacterial cells: targeting multiple-drug resistant transporters. Analytical Chemistry, 86(20), 10114–10121.
4. Wang, F., Chen, F., Ding, F., Zhang, J., Li, Z., & Gao, D. (2013). Super-resolution real-time imaging of multi-drug resistant transporters in living bacterial cells. Journal of the American Chemical Society, 135(47), 17743–17746.
5. Wang, F., Chen, F., Ding, F., et al. (2012). Probing the conformation and dynamics of the MexB multidrug transporter in living cells. Chemical Communications, 48(92), 11331–11333.

 

Last Updated on October 03, 2025