International Journal of Cytokine

International Journal of Cytokine

International Journal of Cytokine – About

Open Access & Peer-Reviewed

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About the International Journal of Cytokine

A peer-reviewed, open access journal advancing molecular understanding of cytokine biology—from signal transduction cascades to gene regulation networks that control cell fate, differentiation, and intercellular communication.

Decoding the Molecular Language of Cytokines

The International Journal of Cytokine (IJCY) serves as a premier platform for researchers dissecting the molecular mechanisms by which cytokines orchestrate cellular behavior. As open access, peer-reviewed scholarship, IJCY publishes groundbreaking discoveries that illuminate how these signaling molecules regulate gene expression, protein interactions, metabolic pathways, and cell differentiation programs across physiological and pathological contexts.

IJCY's editorial mission prioritizes mechanistic rigor and molecular depth—focusing on the fundamental biology of cytokine signaling rather than clinical endpoints. We welcome studies employing genomics, proteomics, structural biology, systems biology, and advanced molecular techniques to unravel cytokine-mediated processes at the cellular and subcellular level. By maintaining strict disciplinary boundaries, IJCY ensures that published content advances foundational knowledge in molecular and cellular biology.

Published by Open Access Pub, IJCY operates under Creative Commons Attribution (CC BY 4.0) licensing, ensuring global accessibility for researchers, educators, and students exploring cytokine biology. Our transparent peer review process, coupled with rapid publication timelines, accelerates knowledge dissemination within the molecular biology community.

Rapid Review Expert Molecular Evaluation
Open Access Unrestricted Global Readership
Mechanistic Focus Molecular-Level Insights
Why Molecular Biologists Choose IJCY

Cytokines represent a diverse family of signaling molecules whose biological impact depends on intricate molecular interactions—receptor binding kinetics, downstream signaling cascades, transcriptional regulation, and post-translational modifications. IJCY provides a focused venue for research that dissects these processes using cutting-edge molecular approaches.

Our editorial board comprises biochemists, molecular biologists, structural biologists, and bioinformaticians who evaluate manuscripts for mechanistic rigor, experimental validity, and contribution to fundamental understanding of cytokine biology. We prioritize studies that advance molecular knowledge through techniques such as CRISPR-based gene editing, proteomics, crystallography, single-cell sequencing, computational modeling, and live-cell imaging.

IJCY's peer review process emphasizes reproducibility, appropriate controls, statistical rigor, and clear delineation between molecular observations and speculative interpretations. Accepted articles undergo thorough editorial refinement to ensure clarity, precision, and accessibility for the broader molecular biology community.

Scope Discipline: IJCY focuses exclusively on molecular mechanisms and cellular processes. We publish research on gene regulation, protein structure-function relationships, signaling pathway analysis, and molecular interactions. Clinical applications, patient outcomes, therapeutic efficacy, and disease management fall outside our scope.
Research Areas Within IJCY's Molecular Focus

IJCY welcomes original research, methodological innovations, and comprehensive reviews that advance molecular understanding of cytokine biology. Our coverage spans the breadth of molecular investigation while maintaining disciplinary coherence.

Signal Transduction Mechanisms

Molecular characterization of cytokine receptor activation, JAK-STAT pathways, MAPK cascades, PI3K-AKT signaling, NF-?B regulation, and cross-talk between signaling networks.

Gene Regulation & Transcriptional Control

Cytokine-induced transcription factor activation, chromatin remodeling, epigenetic modifications, enhancer-promoter interactions, and non-coding RNA regulation.

Protein Structure & Molecular Interactions

Structural biology of cytokines and receptors, binding interface analysis, conformational dynamics, protein-protein interactions, and structure-function relationships.

Cell Differentiation Programming

Molecular mechanisms of cytokine-directed cell fate decisions, lineage commitment, differentiation signaling networks, and transcriptional hierarchies.

Cell Growth & Proliferation Control

Cytokine regulation of cell cycle machinery, growth factor signaling integration, metabolic reprogramming, and molecular checkpoints.

Embryonic Development Pathways

Cytokine roles in developmental signaling cascades, morphogen gradients, tissue patterning, cell migration, and organogenesis at the molecular level.

Tumorigenesis Molecular Mechanisms

Cytokine contributions to oncogenic signaling, tumor microenvironment cell-cell communication, growth dysregulation, and metastatic molecular pathways.

Omics Approaches to Cytokine Biology

Genomics, transcriptomics, proteomics, metabolomics, and systems biology analyses revealing cytokine-regulated molecular networks and cellular responses.

Post-Translational Modifications

Phosphorylation, ubiquitination, glycosylation, and other modifications affecting cytokine and receptor function, stability, localization, and signaling output.

Rigorous Peer Review for Molecular Research

Every submission to IJCY undergoes evaluation by molecular biology specialists who assess experimental design, technical methodology, data quality, statistical analysis, and mechanistic interpretation. Our single-blind peer review process ensures thorough scrutiny while maintaining constructive, actionable feedback.

  • Molecular Methodology Assessment: Reviewers evaluate experimental techniques, appropriate controls, reproducibility measures, and technical rigor specific to molecular biology approaches.
  • Data Quality Standards: Scrutiny of raw data presentation, quantification methods, statistical analyses, sample sizes, and reproducibility across biological replicates.
  • Mechanistic Interpretation: Evaluation of whether conclusions are justified by molecular evidence, avoiding over-interpretation or unsubstantiated mechanistic claims.
  • Scope Alignment: Verification that content focuses on molecular mechanisms rather than clinical applications, ensuring disciplinary coherence.
Reviewer Excellence: IJCY seeks molecular biology experts who can provide insightful technical evaluation. Researchers interested in contributing to the peer review process can explore our reviewer registration and consult our reviewer guidelines for molecular research evaluation criteria.
Streamlined Submission for Molecular Researchers

IJCY's manuscript submission process is designed for efficiency without compromising quality. Researchers can submit through our online portal or via email to [email protected]. Editorial staff provide clear communication throughout the review process, with typical first decisions delivered within 2-3 weeks.

Submission Essentials:
  1. Review IJCY's Aims & Scope to confirm molecular focus alignment before submission.
  2. Consult Instructions for Authors for formatting, methodology reporting, and data presentation requirements.
  3. Prepare manuscripts highlighting molecular mechanisms, including detailed methods enabling reproducibility.
  4. Include appropriate molecular biology controls, statistical analyses, and clear distinction between experimental observations and interpretive conclusions.
  5. Submit via the submission portal with all supplementary data, molecular structure files, and raw data as appropriate.

Authors requiring language refinement can access IJCY's language editing service. Research groups publishing multiple molecular biology studies may benefit from institutional membership packages offering publication fee discounts.

Open Access, Ethics & Data Transparency

IJCY publishes all content under Creative Commons Attribution 4.0 International (CC BY 4.0), enabling unrestricted access, sharing, and adaptation with proper attribution. This licensing model accelerates knowledge dissemination and facilitates meta-analyses, computational studies, and educational use.

Our editorial policies align with COPE (Committee on Publication Ethics) standards and emphasize transparency in molecular research. We encourage authors to deposit molecular data in appropriate repositories (e.g., protein structures in PDB, gene expression data in GEO, proteomics in PRIDE) and cite accession numbers within manuscripts. Detailed information is available on our data archiving page.

Article processing charges apply only after manuscript acceptance. For complete pricing information, waiver eligibility, and institutional agreements, visit the APC information page. IJCY supports early-career researchers and scientists from resource-limited settings through discretionary fee support.

Research Integrity: IJCY's editorial policies require proper experimental ethics approval where applicable, full disclosure of funding sources and conflicts of interest, and adherence to molecular biology community standards for data reporting and reagent documentation.
Visibility Across Molecular Biology Networks

IJCY articles benefit from strategic indexing and discoverability optimization across platforms frequented by molecular biologists, biochemists, and cell biologists. Our distribution ensures broad visibility within specialized and multidisciplinary research communities.

  • Molecular Biology Databases: Strategic indexing in discipline-specific repositories and academic search systems.
  • Academic Platforms: Google Scholar, Semantic Scholar, ResearchGate, and Academia.edu for researcher-to-researcher discovery.
  • Institutional Integration: University library catalogs and research portals worldwide, facilitating access for students and faculty.
  • Specialized Networks: Visibility within cytokine research communities, signal transduction networks, and molecular biology forums.

IJCY maintains active communication with the molecular biology community through our Call for Papers, spotlighting emerging topics in cytokine molecular biology and inviting contributions from researchers advancing mechanistic understanding.

Advance Cytokine Molecular Biology with IJCY

Whether you're elucidating signaling cascades, mapping protein interaction networks, or employing omics approaches to decode cytokine function, IJCY provides a focused publication venue dedicated to molecular-level discovery. Join a community committed to mechanistic rigor and foundational science.

Contact IJCY: Questions about scope alignment, submission requirements, or molecular methodology reporting? Contact our editorial office at [email protected]. We're committed to supporting molecular biologists throughout the publication process.