Malabsorption is the impaired absorption of one or more nutrients across the small-intestinal mucosa, resulting from defects in the digestion, mucosal uptake, or transport of carbohydrates, fats, proteins, vitamins, or minerals. It may be global, affecting many nutrients, or selective, involving a single nutrient, a…
Malabsorption is the impaired absorption of one or more nutrients across the small-intestinal mucosa, resulting from defects in the digestion, mucosal uptake, or transport of carbohydrates, fats, proteins, vitamins, or minerals. It may be global, affecting many nutrients, or selective, involving a single nutrient, and it arises from mucosal disease, enzyme or bile-acid deficiency, surgical alteration of the gut, infection, or impaired motility. Clinical consequences include weight loss, growth faltering in children, steatorrhea, anemia, and specific micronutrient deficiency states. Research relevant to this area examines the clinical use of peptide-based and elemental formulas in pediatric and gastrointestinal disease, where partially hydrolyzed or amino-acid-based nutrition supports uptake when normal digestion is compromised. Related work addresses nutritional deficiencies arising after surgery for morbid obesity, vitamin B12 deficiency due to inadequate intake or absorption, and the impact of intestinal helminth infection on malnutrition and hematological indices in children. Feeding algorithms for vulnerable patients, such as those undergoing haematopoietic stem cell transplantation, and the handling of nutrients such as folic acid also bear on the management of compromised absorption. The field integrates gastroenterology, clinical nutrition, and pediatrics to identify the cause of impaired nutrient uptake and to correct the resulting deficiencies through targeted dietary and medical intervention.
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 7 articles above have been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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