Research Topic · Peer-Reviewed

Antibody Response

The antibody response is the adaptive humoral immune process by which the body, on encountering an antigen, produces specific immunoglobulins to recognize and neutralize it. It depends on B-cell activation, usually with T-helper-cell assistance, followed by clonal proliferation, germinal-center reactions, immunoglob…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 35× across the literature 🗓 Reviewed July 2026

Overview

The antibody response is the adaptive humoral immune process by which the body, on encountering an antigen, produces specific immunoglobulins to recognize and neutralize it. It depends on B-cell activation, usually with T-helper-cell assistance, followed by clonal proliferation, germinal-center reactions, immunoglobulin class switching, and affinity maturation through somatic hypermutation, allowing the immune system to discriminate self from non-self. A primary response generates IgM and subsequently IgG, whereas a secondary response driven by memory B cells is more rapid, of higher affinity, and of greater magnitude, providing the durable protection that vaccination seeks to elicit. The response is characterized by antibody titer, seroconversion, neutralizing activity, and immunoglobulin class, and these measures inform evaluation of vaccine efficacy and population seroprevalence. Antibody responses defend against viral and bacterial infection and can be assessed by serological and immunoassay methods. The research reflected here addresses immune responses to vaccination in calves and human cohorts, neutralizing antibodies in immune plasma, COVID-19 vaccine efficacy and post-vaccination seroprevalence, serological testing, and the enzyme-linked immunosorbent assay. The journal publishes peer-reviewed studies on humoral immunity, vaccine-induced antibody responses, and serological and immunoassay-based assessment across human and veterinary settings.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2024

Splenectomy Reports

Uluc GünayCorresponding author
Exact topic Spleen And Liver Research doi:10.14302/issn.2578-2371.jslr-24-5157

How this research is being cited

The 12 articles above have been cited 35 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Antibody Response, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Antibiotic Research.

Journal editorial board
Tonmoy Debnath · Taiwan Haihong Hao · United States Tauqeer Hussain Mallhi · Australia

This page summarises published research for orientation; it is not medical or professional advice.