Antiretroviral therapy (ART) is the use of combinations of medications to treat infection with the human immunodeficiency virus (HIV) by suppressing viral replication, lowering viral load, and supporting immune recovery to delay disease progression. Effective regimens, frequently referred to as highly active antiret…
Antiretroviral therapy (ART) is the use of combinations of medications to treat infection with the human immunodeficiency virus (HIV) by suppressing viral replication, lowering viral load, and supporting immune recovery to delay disease progression. Effective regimens, frequently referred to as highly active antiretroviral therapy (HAART), pair drugs from multiple classes so the virus is blocked at several points in its replication cycle, which improves the durability of suppression and reduces the likelihood of resistance. ART does not cure HIV, but consistent long-term use can keep the virus undetectable, rebuild CD4 T-cell counts, and markedly reduce onward transmission. In Family Medicine, ART is delivered as part of continuous, comprehensive primary care, including initiation, adherence support, routine monitoring, and management of comorbidities and side effects across the lifespan. The journal's articles in this area address patterns of HAART prescribing and the frequency and direct costs of adverse drug reactions, when and how to measure adherence in resource-limited settings, and the psychosocial determinants of treatment adherence. Additional work covers modeling of long-term CD4 cell-count change, HIV drug resistance in children and adolescents, disclosure of diagnosis to children receiving treatment, antiretroviral-associated peripheral neuropathy, cardiovascular and respiratory findings in treated patients, and the adoption of simplified two-drug regimens.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 34 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Antiretroviral Therapy, linking to each citing work.