Neurotoxicity is the capacity of certain substances to cause harmful, often adverse changes to the structure or function of the nervous system. Neurotoxic agents can disrupt many aspects of nervous-system biology, including the integrity of nerve cells, the balance of neurotransmitters, energy metabolism, oxidative-…
Neurotoxicity is the capacity of certain substances to cause harmful, often adverse changes to the structure or function of the nervous system. Neurotoxic agents can disrupt many aspects of nervous-system biology, including the integrity of nerve cells, the balance of neurotransmitters, energy metabolism, oxidative-stress defenses, and the development and survival of neurons. Exposure may arise from heavy metals, pesticides, industrial chemicals, certain drugs and anesthetics, and naturally occurring toxins, and the resulting effects range from subtle cognitive or sensory changes to permanent neurological damage. Studying neurotoxicity involves identifying which substances cause injury, the cellular and molecular mechanisms involved, and strategies to protect or rescue neural tissue. Research published through Experimental and Clinical Toxicology addresses these questions directly, including studies of quercetin attenuating manganese-induced neurotoxicity in the hippocampus through control of oxidative stress, the dual neuroprotective and neurotoxic effects of general anesthetics on neural stem cells, the protective effect of NNC55-0396 against bupivacaine-induced cell damage, the ameliorative potential of chlorogenic acid against rotenone-induced neurotoxicity in a fruit-fly model, and formulation of a neuroprotective agent. This page gathers peer-reviewed, open-access scholarship relevant to neurotoxicity, its mechanisms, and approaches to neuroprotection.
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 9 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Neurotoxicity, linking to each citing work.