Overview
Antimicrobial resistance (AMR) is the capacity of microorganisms—bacteria, fungi, viruses, and parasites—to survive exposure to drugs that previously inhibited or killed them, rendering standard therapies ineffective. Resistance arises through mutation and horizontal gene transfer, and is propagated by selective pressure from antimicrobial use in human medicine, agriculture, and veterinary practice. Bacterial mechanisms include enzymatic drug inactivation, such as carbapenemase production in Klebsiella pneumoniae and Escherichia coli; target modification; efflux pumps; and biofilm formation that shields organisms, as seen with Salmonella Typhi on gallstones. AMR drives prolonged illness, treatment failure, and mortality, and its containment depends on surveillance of susceptibility patterns, antimicrobial stewardship, infection prevention, and rational prescribing. Drivers include self-medication, inappropriate prescribing for viral and respiratory infections, and antibiotic exposure linked to other infections. Research relevant to this area examines situational analyses of resistance, antimicrobial stewardship knowledge and practice among prescribers, carbapenem resistance in Klebsiella, fecal shedding and biofilm formation by Salmonella Typhi, susceptibility testing of bacterial isolates, antibiotic prescribing for respiratory tract infection, and self-medication practices. This peer-reviewed literature reflects the microbiological mechanisms, epidemiology, and stewardship responses central to confronting antimicrobial resistance as a global public-health threat.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Knowledge, Attitudes and Practices of Prescribers towards Antimicrobial Stewardship at Hospitals in Khartoum State - Sudan
Growing Threat Increased Carbapenem-Resistance among Klebsiella pneumoniae; Antibiotic Susceptibility Pattern of Klebsiella pneumoniae in a Tertiary Care Hospital
Morpho-biochemical Identification and Antimicrobial Susceptibility Testing of Bacterial Isolates from Chicken Eggs in District Faisalabad
Genotypic Diversity among Salmonella Typhi Isolated from Children Living in Informal Settlements in Nairobi, Kenya
Malaria: A Driving Force to the Emergence and the Global Spread of Antibiotics Resistance
Assessment of Self Medication Practice and Drugs Storage Among South Sudanese Community in Addis Ababa, Ethiopia
Conclusion from the Doctor's Dissertation Martynov V.L. on Surgical Correction of Digestive System Refluxes
Antibiotic Prescribing Practices for Upper Respiratory Tract Infection Among Clinical Officers at Kiambu County
Investigation of Antimicrobial Activity of the Extracts of the Leaves, Stembark and Root of Allanblackia floribunda: An Alternative Paradigm Shift Outcome.
Detection of carbapenem resistance mechanisms among Avian Pathogenic Escherichia coli (APEC) isolated from broiler chickens
How this research is being cited
The 12 articles above have been cited 34 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Infection
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2025 · BMC Infectious Diseases
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Lidya Hafidzah Putri et al. · 2025 · JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice)
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Factors influencing irresponsible self-medication in rural Ethiopia: Insights from Gimbichu district2025 · Journal of Public Health in Africa
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2025 · PLOS One
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2025 · Frontiers in Microbiology
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2025 · Open Forum Infectious Diseases
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2025 · Frontiers in Microbiology
A sample of recent works citing this journal's research on Antimicrobial Resistance, linking to each citing work.