Research Topic · Peer-Reviewed

Chronic Infection

Chronic infection is an infection that persists over an extended period, sometimes months or years, when the immune system fails to clear the pathogen and the organism establishes a long-term presence in host tissues. It can be caused by bacteria, viruses, fungi, or parasites, and may remain latent, smouldering, or …

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 47× across the literature 🔖 ISSN 2691-8862 🗓 Reviewed July 2026

Overview

Chronic infection is an infection that persists over an extended period, sometimes months or years, when the immune system fails to clear the pathogen and the organism establishes a long-term presence in host tissues. It can be caused by bacteria, viruses, fungi, or parasites, and may remain latent, smouldering, or intermittently active, producing ongoing tissue damage, immune activation, and in some cases progression to organ failure or malignancy. Mechanisms of persistence include immune evasion, antigenic variation, intracellular survival, and the formation of reservoirs. Research in this area examines bacterial and spirochetal persistence, as in long-standing attention to Lyme disease, and chronic viral hepatitis, including the treatment of chronic hepatitis B with tenofovir and the prevention practices surrounding hepatitis B exposure. Parasitic and zoonotic chronic infection features in work on coinfection by Fasciola hepatica and Mycobacterium bovis in bovine tuberculosis diagnosis and on cytokine responses in pregnant women with toxoplasmosis, while transmission modelling of typhoid fever and hypothesized T-cell vaccination strategies against HIV-1 address the persistence and control of chronic pathogens. The journal publishes peer-reviewed research on the pathogenesis, immunology, and management of persistent infection. Chronic infection matters because it is a major and sustained source of morbidity, mortality, and healthcare burden worldwide.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 47 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Chronic Infection, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Current Viruses and Treatment Methodologies (ISSN 2691-8862).

Journal editorial board
Dr. Anantha Harijith · United States

This page summarises published research for orientation; it is not medical or professional advice.