Overview
Environmental biomarkers are measurable biological indicators that reflect an organism's exposure to environmental agents, the internal dose received, or the resulting biological effects. Measured in tissues, cells, or biological fluids, they translate external environmental conditions into quantifiable molecular, cellular, or physiological signals, and they are conventionally classified as biomarkers of exposure, of effect, and of susceptibility. By capturing the integrated impact of chemical, physical, and dietary exposures, they provide objective evidence linking environmental factors to health outcomes, including the initiation and progression of cancer. Analytical platforms underpin this field: metabolomics characterizes shifts in small-molecule profiles associated with environmental exposure, while liquid and gas chromatography coupled to mass spectrometry enable sensitive detection of contaminants and their biological signatures in samples relevant to food safety and human health. Molecular and epigenetic biomarkers, such as exposure-related DNA methylation changes documented in head and neck cancer, and circulating species like plasma microRNAs that track tumor status, illustrate how environmental influences can be read out at the molecular level. Research in this area develops and validates biomarkers for monitoring exposure, assessing risk, and stratifying susceptible individuals, and increasingly integrates them into cancer-genetics frameworks. Understanding environmental biomarkers supports exposure assessment, etiological investigation, regulatory toxicology, and the identification of modifiable factors that contribute to disease.
Research published in this journal
6 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Epigenetic Biomarkers in Head and Neck Cancer
Molecular Biomarkers: A Brief Review
Liquid Chromatography-Mass Spectrometry (LC-MS) Applications in Food Safety–Review
Dynamic MicroRNA-Expression in Plasma of Melanoma Patients Correlates With Progression, PD-L1 Status and Overall Survival
High-Throughput Complex Disease Modeling for Ethical Drug Discovery: Clinical Relevance of a NAM Platform for Cancer Biomarker Development
How this research is being cited
The 6 articles above have been cited 12 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Human Gene
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Maria Constantin et al. · 2024 · Frontiers in Oncology
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2024 · Biomedical Research and Therapy
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2023 · Medical Oncology
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S. Kurevlev et al. · 2023 · Head and Neck Tumors (HNT)
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2023 · Medical Oncology
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2023 · Head and neck tumors (HNT)
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2023 ·
A sample of recent works citing this journal's research on Environmental Biomarkers, linking to each citing work.