Protein expression is the cellular process by which the information encoded in a gene is converted into a functional protein, encompassing transcription of DNA into messenger RNA, translation of that message into a polypeptide, and the folding and post-translational modification that yield a mature molecule. The lev…
Protein expression is the cellular process by which the information encoded in a gene is converted into a functional protein, encompassing transcription of DNA into messenger RNA, translation of that message into a polypeptide, and the folding and post-translational modification that yield a mature molecule. The level and timing of expression are tightly regulated by transcription factors, signalling pathways, RNA stability, and microenvironmental cues, so that a single genome gives rise to distinct proteomes across cell types and conditions. In biotechnology, controlled protein expression in bacterial, yeast, insect, or mammalian host systems underpins the production of enzymes, therapeutics, and research reagents, while the measurement of endogenous expression is fundamental to understanding disease mechanisms. Research indexed under this topic examines how protein expression changes in response to mechanical, inflammatory, and stress stimuli, including the influence of substrate stiffness, drought and salinity stress in plants, and signalling through factors such as transcription factor EB and NF-kB. It also covers comparative proteomic profiling, overexpression studies relevant to cancer progression and metastasis, and the role of regulatory RNAs in modulating expression. Techniques include quantitative proteomics, immunodetection, transcriptomic analysis, and digital PCR. The peer-reviewed work here connects molecular and cellular biology with biomedical and biotechnological application, illuminating how gene expression governs phenotype and pathology.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 79 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Protein Expression, linking to each citing work.