Overview
Advanced Pharmaceutical Science And Technology is a rapidly developing field that requires continuous research and development. Non-clinical medicine research is an essential part of this field. It encompasses the methodology and techniques used for evaluating drugs at the preclinical stage. This process also involves identifying potential drug targets, determining the therapeutic dose range, assessing the safety and pharmacokinetics of a drug candidate, and finally, selecting the best drug candidates for clinical trials. The non-clinical research process involves in vitro and in vivo experiments that aim to understand the behavior of a drug candidate in the body. In vitro testing is carried out on cultured cells or tissues. This helps researchers to understand how the drug interacts with a specific cell type or organ. In vivo tests use animal models to test the efficacy and safety of a drug candidate. The study of pharmacokinetics is another critical aspect of non-clinical research. It evaluates how a drug is absorbed, distributed, metabolized, and excreted. This includes determining the half-life of the drug, the maximum concentration that can be achieved, and the presence of any toxic metabolites. Non-clinical research also involves conducting safety studies for pharmaceuticals. Toxicology studies help researchers to understand potential safety concerns such as acute and chronic toxicity, teratogenicity, and carcinogenicity. This enables researchers to generate safety data required by regulatory agencies that would approve a drug candidate for clinical use. In summary, non-clinical medicine research is a critical component of Advanced Pharmaceutical Science And Technology. It is essential to ensure that the drugs developed are safe and effective for clinical use. The use of reliable and innovative non-clinical research methods lays the foundation for the success of the entire pharmaceutical industry.
Research published in this journal
4 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Assessment of Self Medication Practice and Drugs Storage Among South Sudanese Community in Addis Ababa, Ethiopia
Invivo Impact of Malaria and HIV Co-Infection on CD4 Cell Count of Infected Patients of Niger Delta Extraction
Proximate, Mineral and Antinutrient Compositions of Natural Cocoa Cake, Cocoa Liquor and Alkalized Cocoa Powders Sourced in Nigeria
How this research is being cited
The 4 articles above have been cited 41 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Applied Food Research
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2025 · Journal of Food Composition and Analysis
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2025 · Food Biophysics
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2025 · Journal of Food Composition and Analysis
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2025 · Journal of Food Composition and Analysis
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Factors influencing irresponsible self-medication in rural Ethiopia: Insights from Gimbichu district2025 · Journal of Public Health in Africa
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Maurizio Asfalto et al. · 2025 · Italian Journal of Food Science
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2024 · Food Research International
A sample of recent works citing this journal's research on Non-Clinical Medicine Research Methods, linking to each citing work.